FIRST RECORD OF SALMONELLA PARATYPHI B IN A CAPTIVE CORN SNAKE IN BULGARIA – CASE REPORT
DOI:
https://doi.org/10.15547/tjs.2026.01.008Keywords:
Corn snake, Salmonella Paratyphi B, Vitek 2 Compact, zoonosis, antimicrobial resistanceAbstract
This report presents a case of an adult captive corn snake (Pantherophis guttatus) displaying symptoms of gastrointestinal disorders, including anorexia, diarrhoea, and lethargy. Diagnostic testing using the Vitec 2 Compact System confirmed the presence of Salmonella Paratyphi B, а zoonotic pathogen which poses a health risk to both the snake and the humans. Antimicrobial susceptibility testing revealed resistance to cefalexin, gentamicin and amikacin, common veterinary antibiotics, but susceptibility to levofloxacin, ceftazidime, ciprofloxacin, and trimethoprim/sulfamethoxazole which could be used for treatment. This case highlights the zoonotic risks associated with Salmonella in reptiles and the need for regular microbiological monitoring to ensure snakes’ well-being and public health. It emphasizes the importance of responsible husbandry and veterinary care in preventing the spread of antimicrobial resistance.
References
Pees, M., Brockmann, M., Steiner, N., and Marschang, R. E. Salmonella in reptiles: a review of occurrence, interactions, shedding and risk factors for human infections. Frontiers in cell and developmental biology, 11, 1251036, 2023.
Zając, M., Skarżyńska, M., Lalak, A., Kwit, R., Śmiałowska-Węglińska, A., Pasim, P., and Wasyl, D. Salmonella in captive reptiles and their environment—can we tame the dragon?. Microorganisms, 9(5), 1012, 2021.
Bjelland, A. M., Sandvik, L. M., Skarstein, M. M., Svendal, L., and Debenham, J. J. Prevalence of Salmonella serovars isolated from reptiles in Norwegian zoos. Acta Veterinaria Scandinavica, 62(1), 3, 2020.
Meletiadis, A., Biolatti, C., Mugetti, D., Zaccaria, T., Cipriani, R., Pitti, M., Decastelli, L., Cimino, F., Dondo, A., Maurella, C., Bozzetta, E., and Acutis, P. L. Surveys on Exposure to Reptile-Associated Salmonellosis (RAS) in the Piedmont Region—Italy. Animals, 12(7), 906, 2022. https://doi.org/10.3390/ani12070906,
Sanders ER.Aseptic laboratory techniques: plating methods. J Vis Exp JoVE 63:e3064, 2012.
Funke, G., & Funke-Kissling, P. (2004). Evaluation of the new VITEK 2 card for identification of clinically relevant gram-negative rods. Journal of clinical microbiology, 42(9), 4067-4071. (Sanders ER (2012) Aseptic laboratory techniques: plating methods. J Vis Exp JoVE 63:e3064)
Grimont, P. A., and Weill, F. X. Antigenic formulae of the Salmonella serovars. WHO collaborating centre for reference and research on Salmonella, 9, 1-166, 2007.
Claunch, N. M., Lind, C., Lutterschmidt, D. I., Moore, I. T., Neuman-Lee, L., Stahlschmidt, Z., and Penning, D. Stress ecology in snakes. editor Penning D. Snakes. Nova Science Publishers, Inc, 415-478, 2023.
Khan, H. A., Almalki, M. H., Felemban, R., Elbanna, K., and Abulreesh, H. H. Antibiotic-resistant salmonellae in pet reptiles in Saudi Arabia. Microbiology Independent Research journal, 9(1), 31-36, 2022.
Mancera, K. F., and Phillips, C. J. Effects of noise and light. In Health and welfare of captive reptiles (pp. 357-378). Cham: Springer International Publishing, 2023.
Basiouni, S., Rodriguez-Morales, A. J., Shehata, A. A., and Duarte, P. M. Silent Carriers: The Role of Rodents in the Emergence of Zoonotic Bacterial Threats. Pathogens, 14(9), 928, 2025.
Fankhauser, G., and Cumming, K. B. Snake hybridization: A case for intrabaraminic diversity. In Proceedings of the International Conference on Creationism (Vol. 6, No. 1, p. 13), 2008.
Clark, M. I., Hileman, E. T., Moore, J. A., Faust, L. J., Junge, R. E., Reid, B. N., and Fitzpatrick, S. W. Inbreeding reduces fitness in spatially structured populations of a threatened rattlesnake. Proceedings of the National Academy of Sciences, 122(34), e2501745122, 2025.
Cristina, R. T., Kocsis, R., Dégi, J., Muselin, F., Dumitrescu, E., Tirziu, E., and Oprescu, I. Pathology and prevalence of antibiotic-resistant bacteria: a study of 398 pet reptiles. Animals, 12(10), 1279,2022.
Kitchens, S. R., Wang, C., and Price, S. B. Bridging classical methodologies in Salmonella investigation with modern technologies: A comprehensive review. Microorganisms, 12(11), 2249, 2024.
Gwenzi, W., Chaukura, N., Muisa-Zikali, N., Teta, C., Musvuugwa, T., Rzymski, P., and Abia, A. L. K. Insects, Rodents, and Pets as Reservoirs, Vectors, and Sentinels of Antimicrobial Resistance. Antibiotics, 10(1),68, 2021. https://doi.org/10.3390/antibiotics10010068
Marin, C., Lorenzo-Rebenaque, L., Laso, O., Villora-Gonzalez, J. and Vega, S. Pet reptiles: a potential source of transmission of multidrug-resistant Salmonella. Frontiers in Veterinary Science, 7, 613718, 2021.
Hedley, J., Whitehead, M. L., Munns, C., Pellett, S., Abou‐Zahr, T., Calvo Carrasco, D., and Wissink‐Argilaga, N. Antibiotic stewardship for reptiles. Journal of Small Animal Practice, 62(10), 829-839, 2021.
Maugeri, G., Lychko, I., Sobral, R. and Roque, A. C. Identification and antibiotic‐susceptibility profiling of infectious bacterial agents: a review of current and future trends. Biotechnology journal, 14(1), 1700750, 2019.
Meletiadis, A., Romano, A., Moroni, B., Di Nicola, M. R., Montemurro, V., Pitti, M., and Acutis, P. L. A case of food-borne salmonellosis in a corn snake (Pantherophis guttatus) after a feeder mouse meal. Animals, 14(12), 1722, 2024.
Pasmans, F., Martel, A. N., and Jacobson, E. R. Bacterial diseases of reptiles. Infectious diseases and Pathology of reptiles, 705-794, 2020.
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